Tractor-Trailer Crash on Interstate 255 Kills 1, Injures 2 [St. Louis County, MO]

St. Louis County, MO (September 11, 2026) — On Wednesday afternoon, a tractor-trailer crash on Interstate 255 in St. Louis County, Missouri, killed one person and injured two others.

According to the Missouri State Highway Patrol, the semi struck an SUV on eastbound I-255 around 2 p.m. The SUV veered off the roadway and hit a concrete barrier, while the tractor-trailer left the highway, crossed the outer road, and crashed into three homes and two parked vehicles.

The 52-year-old truck driver from Jerseyville, Illinois, died at the scene. A 73-year-old woman driving the SUV and a 14-year-old girl riding with her suffered minor injuries.

The collision shut down eastbound I-255 while emergency crews responded and investigated. Residents of the damaged homes escaped safely, although one property sustained extensive damage and may be a total loss.

The Missouri State Highway Patrol continues to investigate the crash.

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Sweet Lawyers extends our deepest condolences and sympathies to the family and loved ones of the 52-year-old truck driver who lost his life. Our hearts are with you through these difficult times.

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