One Seriously Injured in Three-Vehicle Crash on Interstate 55 [Cape Girardeau, MO]

Police Investigate Three-Vehicle Crash on Interstate 55 in Cape Girardeau

CAPE GIRARDEAU, MO (July 17, 2026)— A three-vehicle crash on Interstate 55 seriously injured one person on Friday.

Emergency crews responded shortly before noon to the collision near mile marker 96, according to the Cape Girardeau Police Department.

Medical personnel transported one person to a hospital with serious injuries. Authorities have not released additional information about the injured person’s condition or identified the motorists involved.

The crash occurred beneath the William Street overpass. Police closed the interstate’s southbound lanes while first responders assisted those involved and crews cleared the crash site.

The Missouri Department of Transportation reported that the collision caused traffic delays along the interstate for approximately two hours.

Cape Girardeau police later reopened all southbound lanes to normal traffic.

Officials have not provided further details about what caused the three vehicles to collide.

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A serious multi-vehicle crash can leave an injured person and their family facing a sudden and deeply stressful situation.

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